Why you would want to follow that route

Get on the M3

The M3 guitar is symmetrical

From low to high, the tuning is E-Ab-C-E-Ab-C-E so adjacent strings are tuned in fourth fret all the way up. Since the top and bottom strings are E's two octaves apart, the range of notes at your disposal is the same as on a 6-string guitar in conventional tuning. However, gone is the exceptional interval between the 2nd and 3rd string (four semitones as opposed to five semitones between all other pairs of strings) that breaks the symmetry. On the M3, shapes on the neck repeat every four frets, and octaves repeat every three strings.

The M3 guitar is comfortable to play

You have a finger for each fret no matter which position you are playing in, and you will never have to shift more than two frets up or down to get to your favourite position. It is possible to play chords that use piano-type close voicings. On the whole, however, it is probably fair to say that the M3 relaxes your brain more than your fingers.

On the M3 guitar you play less cliches

Many runs and chords have been played to death on the 6-string guitar in conventional tuning. On the M3 you are not likely to stumble across those chords and runs unless you look for them. The instrument is very different to play mechanically, and it has, of course, its own set of convenient runs and chords, they just haven't been played to death yet. For this reason it is easier to figure out things that sound new and fresh because you don't follow the same line of thinking as that of millions of other guitarists.